You can dynamically change all application program major node operands by editing the VTAMLST member and then issuing the VARY ACT,UPDATE=ALL command.
To dynamically change an operand on the APPL statement, the application must be inactive. You can dynamically change the operands associated with tables (ASLTAB, MDLTAB, and MODETAB) at any time without deactivating resources.
Restriction: Dynamic change of operands does not apply to clone applications.