Ensure you are running on supported servers and storage controllers

z/OS V2R1 runs on these IBM System z servers:
In addition, z/OS V2R1 supports these and later IBM storage control units:
The following IBM servers are no longer supported to run z/OS V2R1: Note that running z/OS V2R1 as a z/VM guest has the same requirements as running natively in an LPAR.
Steps to take:
  1. Determine whether the servers and control units that you use are supported for z/OS V2R1. If you have a question about support for any devices not listed, contact your IBM representative.
  2. Install replacement servers and control units. Detach unsupported servers and control units from the system and delete their corresponding definitions from the input/output definition file (IODF).

Reference: For more information, see Release memorandum - RFA 58183 - 04/15/13 (IBM Guide 27.10).